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Médicament Sibutral (sibutramine, Réductil, Meridia) 

Le SIBUTRAL® est le nom de marque en France de la sibutramine, commercialisée dans d'autres pays sous le nom de REDUCTIL® ou de MERIDIA®. Il s'agit d'un anorexigène sérotoninergique et noradrénergique. Sibutral Réductil et Meridia sont des marques déposées propriété des  laboratoires Knoll

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courbe bleue         Bibliographie (Source : PubMed)

  
 
Hazenberg BP. Related Articles
Randomized, double-blind, placebo-controlled, multicenter study of sibutramine in obese hypertensive patients.
Cardiology. 2000;94(3):152-8.
PMID: 11279320 [PubMed - indexed for MEDLINE]

Martin-Du Pan RC, Heraief E. Related Articles
[Ten questions on the treatment of obesity: from dieting to surgery].
Rev Med Suisse Romande. 2001 Jan;121(1):57-63. Review. French.
PMID: 11234711 [PubMed - indexed for MEDLINE]
 
Fujioka K, Seaton TB, Rowe E, Jelinek CA, Raskin P, Lebovitz HE, Weinstein SP. Related Articles
Weight loss with sibutramine improves glycaemic control and other metabolic parameters in obese patients with type 2 diabetes mellitus.
Diabetes Obes Metab. 2000 Jun;2(3):175-87.
PMID: 11220553 [PubMed - indexed for MEDLINE]
 
Finer N, Bloom SR, Frost GS, Banks LM, Griffiths J. Related Articles
Sibutramine is effective for weight loss and diabetic control in obesity with type 2 diabetes: a randomised, double-blind, placebo-controlled study.
Diabetes Obes Metab. 2000 Apr;2(2):105-12.
PMID: 11220522 [PubMed - indexed for MEDLINE]
 
Keipes M, Fuente Martinez M, Nicolay L, Kuffer V, Mersch L, Klees J, Jacque M. Related Articles
[Evolution and weight and body composition determination after therapy for pathological obesity for measuring compliance in (re)-education].
Bull Soc Sci Med Grand Duche Luxemb. 2000;(1):17-29. French.
PMID: 11200309 [PubMed - indexed for MEDLINE]
 
James WP, Astrup A, Finer N, Hilsted J, Kopelman P, Rossner S, Saris WH, Van Gaal LF. Related Articles
Effect of sibutramine on weight maintenance after weight loss: a randomised trial. STORM Study Group. Sibutramine Trial of Obesity Reduction and Maintenance.
Lancet. 2000 Dec 23-30;356(9248):2119-25.
PMID: 11191537 [PubMed - indexed for MEDLINE]
 
Astrup A. Related Articles
Thermogenic drugs as a strategy for treatment of obesity.
Endocrine. 2000 Oct;13(2):207-12. Review.
PMID: 11186222 [PubMed - indexed for MEDLINE]
 
Ryan DH. Related Articles
Use of sibutramine and other noradrenergic and serotonergic drugs in the management of obesity.
Endocrine. 2000 Oct;13(2):193-9. Review.
PMID: 11186220 [PubMed - indexed for MEDLINE]
 
Wadden TA, Berkowitz RI, Sarwer DB, Prus-Wisniewski R, Steinberg C. Related Articles
Benefits of lifestyle modification in the pharmacologic treatment of obesity: a randomized trial.
Arch Intern Med. 2001 Jan 22;161(2):218-27.
PMID: 11176735 [PubMed - indexed for MEDLINE]
 
12: Proietto J, Fam BC, Ainslie DA, Thorburn AW. Related Articles
Novel anti-obesity drugs.
Expert Opin Investig Drugs. 2000 Jun;9(6):1317-26. Review.
PMID: 11060745 [PubMed - indexed for MEDLINE]
 
13: Bray GA. Related Articles
A concise review on the therapeutics of obesity.
Nutrition. 2000 Oct;16(10):953-60. Review.
PMID: 11054601 [PubMed - indexed for MEDLINE]
 
Heini A. Related Articles
[Contraindications to weight reduction].
Ther Umsch. 2000 Aug;57(8):537-41. Review. German.
PMID: 11026093 [PubMed - indexed for MEDLINE]
 
Imoberdorf R, Ballmer PE. Related Articles
[Obesity: principles of drug therapy].
Ther Umsch. 2000 Aug;57(8):522-5. Review. German.
PMID: 11026090 [PubMed - indexed for MEDLINE]
Wadden TA, Berkowitz RI, Womble LG, Sarwer DB, Arnold ME, Steinberg CM. Related Articles
Effects of sibutramine plus orlistat in obese women following 1 year of treatment by sibutramine alone: a placebo-controlled trial.
Obes Res. 2000 Sep;8(6):431-7.
PMID: 11011909 [PubMed - indexed for MEDLINE]
 
Tonstad S, Birkeland KI. Related Articles
[The obesity epidemics--do diet pills have a place in the treatment]?
Tidsskr Nor Laegeforen. 2000 Jun 30;120(17):1997-2001. Review. Norwegian.
PMID: 11008533 [PubMed - indexed for MEDLINE]
 
Bray GA. Related Articles
Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications.
Int J Obes Relat Metab Disord. 2000 Jun;24 Suppl 2:S8-17. Review.
PMID: 10997600 [PubMed - indexed for MEDLINE]
 
Ziegler O, Quilliot D. Related Articles
[Drug treatment of obesity and type 2 diabetes].
Diabetes Metab. 2000 Jun;26 Suppl 3:34-41. Review. French.
PMID: 10945151 [PubMed - indexed for MEDLINE]
 
Bray GA. Related Articles
Drug treatment of obesity.
Baillieres Best Pract Res Clin Endocrinol Metab. 1999 Apr;13(1):131-48. Review.
PMID: 10932681 [PubMed - indexed for MEDLINE]
 
Berke EM, Morden NE. Related Articles
Medical management of obesity.
Am Fam Physician. 2000 Jul 15;62(2):419-26. Review.
PMID: 10929704 [PubMed - indexed for MEDLINE]
 
Agrawal M, Worzniak M, Diamond L. Related Articles
Managing obesity like any other chronic condition. Long-term therapy may reduce comorbidity as well.
Postgrad Med. 2000 Jul;108(1):75-6, 79-82. Review.
PMID: 10914120 [PubMed - indexed for MEDLINE]
 
McMahon FG, Fujioka K, Singh BN, Mendel CM, Rowe E, Rolston K, Johnson F, Mooradian AD. Related Articles
Efficacy and safety of sibutramine in obese white and African American patients with hypertension: a 1-year, double-blind, placebo-controlled, multicenter trial.
Arch Intern Med. 2000 Jul 24;160(14):2185-91.
PMID: 10904462 [PubMed - indexed for MEDLINE]
 
Kamel EG, McNeill G, Van Wijk MC. Related Articles
Change in intra-abdominal adipose tissue volume during weight loss in obese men and women: correlation between magnetic resonance imaging and anthropometric measurements.
Int J Obes Relat Metab Disord. 2000 May;24(5):607-13.
PMID: 10849583 [PubMed - indexed for MEDLINE]
 
Hirsch J, Mackintosh RM, Aronne LJ. Related Articles
The effects of drugs used to treat obesity on the autonomic nervous system.
Obes Res. 2000 May;8(3):227-33.
PMID: 10832765 [PubMed - indexed for MEDLINE]
 
Suter PM, Vetter W. Related Articles
[Drug therapy of obesity. Strategies for general practice].
Schweiz Rundsch Med Prax. 2000 Mar 30;89(14):575-85. Review. German.
PMID: 10815465 [PubMed - indexed for MEDLINE]
 
Bray GA, Tartaglia LA. Related Articles
Medicinal strategies in the treatment of obesity.
Nature. 2000 Apr 6;404(6778):672-7. Review.
PMID: 10766254 [PubMed - indexed for MEDLINE]
 
Leong KS, Wilding JP. Related Articles
Obesity and diabetes.
Baillieres Best Pract Res Clin Endocrinol Metab. 1999 Jul;13(2):221-37. Review.
PMID: 10761864 [PubMed - indexed for MEDLINE]
 
Scheen AJ. Related Articles
Treatment of diabetes in patients with severe obesity.
Biomed Pharmacother. 2000 Mar;54(2):74-9. Review.
PMID: 10759290 [PubMed - indexed for MEDLINE]
 
Scheen AJ, Lefebvre PJ. Related Articles
Antiobesity pharmacotherapy in the management of type 2 diabetes.
Diabetes Metab Res Rev. 2000 Mar-Apr;16(2):114-24. Review.
PMID: 10751751 [PubMed - indexed for MEDLINE]
 
33: Richter WO. Related Articles
[How safe are the new obesity drugs? Indications and contraindications of orlistat and sibutramine].
MMW Fortschr Med. 1999 Dec 9;141(49-50):32-6. German.
PMID: 10726144 [PubMed - indexed for MEDLINE]
 
34: Chapelot D, Marmonier C, Thomas F, Hanotin C. Related Articles
Modalities of the food intake-reducing effect of sibutramine in humans.
Physiol Behav. 2000 Jan;68(3):299-308.
PMID: 10716539 [PubMed - indexed for MEDLINE]
 
35: Cuellar GE, Ruiz AM, Monsalve MC, Berber A. Related Articles
Six-month treatment of obesity with sibutramine 15 mg; a double-blind, placebo-controlled monocenter clinical trial in a Hispanic population.
Obes Res. 2000 Jan;8(1):71-82.
PMID: 10678261 [PubMed - indexed for MEDLINE]
 
36: Fanghanel G, Cortinas L, Sanchez-Reyes L, Berber A. Related Articles
A clinical trial of the use of sibutramine for the treatment of patients suffering essential obesity.
Int J Obes Relat Metab Disord. 2000 Feb;24(2):144-50.
PMID: 10702763 [PubMed - indexed for MEDLINE]
 
37: Schuh LM, Schuster CR, Hopper JA, Mendel CM. Related Articles
Abuse liability assessment of sibutramine, a novel weight control agent.
Psychopharmacology (Berl). 2000 Jan;147(4):339-46.
PMID: 10672626 [PubMed - indexed for MEDLINE]
 
38: Wesnes KA, Garratt C, Wickens M, Gudgeon A, Oliver S. Related Articles
Effects of sibutramine alone and with alcohol on cognitive function in healthy volunteers.
Br J Clin Pharmacol. 2000 Feb;49(2):110-7.
PMID: 10671904 [PubMed - indexed for MEDLINE]
 
39: Wangsness M. Related Articles
Pharmacological treatment of obesity. Past, present, and future.
Minn Med. 2000 Nov;83(11):21-6. Review.
PMID: 11126476 [PubMed - indexed for MEDLINE]
 
40: Taflinski T, Chojnacka J. Related Articles
Sibutramine-associated psychotic episode.
Am J Psychiatry. 2000 Dec;157(12):2057-8. No abstract available.
PMID: 11097984 [PubMed - indexed for MEDLINE]
 
41: Danforth E Jr. Related Articles
Sibutramine and thermogenesis in humans.
Int J Obes Relat Metab Disord. 1999 Oct;23(10):1007-8. Review. No abstract available.
PMID: 10557019 [PubMed - indexed for MEDLINE]
 
42: Hansen DL, Toubro S, Stock MJ, Macdonald IA, Astrup A. Related Articles
The effect of sibutramine on energy expenditure and appetite during chronic treatment without dietary restriction.
Int J Obes Relat Metab Disord. 1999 Oct;23(10):1016-24.
PMID: 10557021 [PubMed - indexed for MEDLINE]
 
43: Walsh KM, Leen E, Lean ME. Related Articles
The effect of sibutramine on resting energy expenditure and adrenaline-induced thermogenesis in obese females.
Int J Obes Relat Metab Disord. 1999 Oct;23(10):1009-15.
PMID: 10557020 [PubMed - indexed for MEDLINE]
 
44: Greenberg I, Chan S, Blackburn GL. Related Articles
Nonpharmacologic and pharmacologic management of weight gain.
J Clin Psychiatry. 1999;60 Suppl 21:31-6. Review.
PMID: 10548140 [PubMed - indexed for MEDLINE]
 
45: Luque CA, Rey JA. Related Articles
Sibutramine: a serotonin-norepinephrine reuptake-inhibitor for the treatment of obesity.
Ann Pharmacother. 1999 Sep;33(9):968-78. Review.
PMID: 10492502 [PubMed - indexed for MEDLINE]
 
46: Hauner H. Related Articles
The impact of pharmacotherapy on weight management in type 2 diabetes.
Int J Obes Relat Metab Disord. 1999 Jun;23 Suppl 7:S12-7. Review.
PMID: 10455466 [PubMed - indexed for MEDLINE]
 
47: Williams G. Related Articles
Obesity and type 2 diabetes: a conflict of interests?
Int J Obes Relat Metab Disord. 1999 Jun;23 Suppl 7:S2-4. Review.
PMID: 10455464 [PubMed - indexed for MEDLINE]
 
48: Bach DS, Rissanen AM, Mendel CM, Shepherd G, Weinstein SP, Kelly F, Seaton TB, Patel B, Pekkarinen TA, Armstrong WF. Related Articles
Absence of cardiac valve dysfunction in obese patients treated with sibutramine.
Obes Res. 1999 Jul;7(4):363-9.
PMID: 10440592 [PubMed - indexed for MEDLINE]
 
49: Carek PJ, Dickerson LM. Related Articles
Current concepts in the pharmacological management of obesity.
Drugs. 1999 Jun;57(6):883-904. Review.
PMID: 10400403 [PubMed - indexed for MEDLINE]
 
50: Maughan KL. Related Articles
Does sibutramine keep the weight off?
J Fam Pract. 1999 Jun;48(6):420. No abstract available.
PMID: 10386483 [PubMed - indexed for MEDLINE]
 
51: Apfelbaum M, Vague P, Ziegler O, Hanotin C, Thomas F, Leutenegger E. Related Articles
Long-term maintenance of weight loss after a very-low-calorie diet: a randomized blinded trial of the efficacy and tolerability of sibutramine.
Am J Med. 1999 Feb;106(2):179-84.
PMID: 10230747 [PubMed - indexed for MEDLINE]
 
52: Scheen AJ, Lefebvre PJ. Related Articles
Pharmacological treatment of obesity: present status.
Int J Obes Relat Metab Disord. 1999 Feb;23 Suppl 1:47-53. Review.
PMID: 10193862 [PubMed - indexed for MEDLINE]
 
53: Bray GA, Blackburn GL, Ferguson JM, Greenway FL, Jain AK, Mendel CM, Mendels J, Ryan DH, Schwartz SL, Scheinbaum ML, Seaton TB. Related Articles
Sibutramine produces dose-related weight loss.
Obes Res. 1999 Mar;7(2):189-98.
PMID: 10102256 [PubMed - indexed for MEDLINE]
 
54: Kolanowski J. Related Articles
A risk-benefit assessment of anti-obesity drugs.
Drug Saf. 1999 Feb;20(2):119-31. Review.
PMID: 10082070 [PubMed - indexed for MEDLINE]
 
55: Hind ID, Mangham JE, Ghani SP, Haddock RE, Garratt CJ, Jones RW. Related Articles
Sibutramine pharmacokinetics in young and elderly healthy subjects.
Eur J Clin Pharmacol. 1999 Jan;54(11):847-9.
PMID: 10027659 [PubMed - indexed for MEDLINE]
 
56: Schusdziarra V. Related Articles
[What is the role of drugs in therapy of obesity]?
Wien Med Wochenschr. 1998;148(17):401-2. Review. German.
PMID: 9887502 [PubMed - indexed for MEDLINE]
 
57: Astrup A. Related Articles
[Sibutramine, an upcoming drug for weight loss acting on energy consumption and energy expenditure].
Acta Med Austriaca. 1998;25(4-5):146-9. Review. German.
PMID: 9879391 [PubMed - indexed for MEDLINE]
 
59: McNeely W, Goa KL. Related Articles
Sibutramine. A review of its contribution to the management of obesity.
Drugs. 1998 Dec;56(6):1093-124. Review.
PMID: 9878996 [PubMed - indexed for MEDLINE]
 
60: Hansen DL, Toubro S, Stock MJ, Macdonald IA, Astrup A. Related Articles
Thermogenic effects of sibutramine in humans.
Am J Clin Nutr. 1998 Dec;68(6):1180-6.
PMID: 9846844 [PubMed - indexed for MEDLINE]
 
61: Van Gaal LF, Wauters MA, De Leeuw IH. Related Articles
Anti-obesity drugs: what does sibutramine offer? An analysis of its potential contribution to obesity treatment.
Exp Clin Endocrinol Diabetes. 1998;106 Suppl 2:35-40. Review.
PMID: 9792480 [PubMed - indexed for MEDLINE]
 
62: Astrup A, Lundsgaard C. Related Articles
What do pharmacological approaches to obesity management offer? Linking pharmacological mechanisms of obesity management agents to clinical practice.
Exp Clin Endocrinol Diabetes. 1998;106 Suppl 2:29-34. Review.
PMID: 9792479 [PubMed - indexed for MEDLINE]
 
63: Aronne LJ. Related Articles
Modern medical management of obesity: the role of pharmaceutical intervention.
J Am Diet Assoc. 1998 Oct;98(10 Suppl 2):S23-6. Review.
PMID: 9787732 [PubMed - indexed for MEDLINE]
 
64: Rissanen A. Related Articles
Pharmacological intervention: the antiobesity approach.
Eur J Clin Invest. 1998 Sep;28 Suppl 2:27-30. Review.
PMID: 9777325 [PubMed - indexed for MEDLINE]
 
65: Wynn RL. Related Articles
Sibutramine (Meridia)--dental considerations for a new weight control drug.
Gen Dent. 1998 Jul-Aug;46(4):332-5. Review. No abstract available.
PMID: 9758977 [PubMed - indexed for MEDLINE]
 
66: Van Gaal LF, Wauters MA, Peiffer FW, De Leeuw IH. Related Articles
Sibutramine and fat distribution: is there a role for pharmacotherapy in abdominal/visceral fat reduction?
Int J Obes Relat Metab Disord. 1998 Aug;22 Suppl 1:S38-40; discussion S41-2.
PMID: 9758242 [PubMed - indexed for MEDLINE]
 
67: Astrup A, Hansen DL, Lundsgaard C, Toubro S. Related Articles
Sibutramine and energy balance.
Int J Obes Relat Metab Disord. 1998 Aug;22 Suppl 1:S30-5; discussion S36-7, S42. Review.
PMID: 9758241 [PubMed - indexed for MEDLINE]
 
68: Heal DJ, Aspley S, Prow MR, Jackson HC, Martin KF, Cheetham SC. Related Articles
Sibutramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine.
Int J Obes Relat Metab Disord. 1998 Aug;22 Suppl 1:S18-28; discussion S29. Review.
PMID: 9758240 [PubMed - indexed for MEDLINE]
 
69: Kurscheid T, Lauterbach K. Related Articles
The cost implications of obesity for health care and society.
Int J Obes Relat Metab Disord. 1998 Aug;22 Suppl 1:S3-5; discussion S6. Review.
PMID: 9758237 [PubMed - indexed for MEDLINE]
 
70: Hanotin C, Thomas F, Jones SP, Leutenegger E, Drouin P. Related Articles
A comparison of sibutramine and dexfenfluramine in the treatment of obesity.
Obes Res. 1998 Jul;6(4):285-91.
PMID: 9688105 [PubMed - indexed for MEDLINE]
 
71: Cole JO, Levin A, Beake B, Kaiser PE, Scheinbaum ML. Related Articles
Sibutramine: a new weight loss agent without evidence of the abuse potential associated with amphetamines.
J Clin Psychopharmacol. 1998 Jun;18(3):231-6.
PMID: 9617982 [PubMed - indexed for MEDLINE]
 
72: Seagle HM, Bessesen DH, Hill JO. Related Articles
Effects of sibutramine on resting metabolic rate and weight loss in overweight women.
Obes Res. 1998 Mar;6(2):115-21.
PMID: 9545017 [PubMed - indexed for MEDLINE]
 
73: [No authors listed] Related Articles
Sibutramine for obesity.
Med Lett Drugs Ther. 1998 Mar 13;40(1022):32. No abstract available.
PMID: 9529518 [PubMed - indexed for MEDLINE]
 
74: Rolls BJ, Shide DJ, Thorwart ML, Ulbrecht JS. Related Articles
Sibutramine reduces food intake in non-dieting women with obesity.
Obes Res. 1998 Jan;6(1):1-11.
PMID: 9526964 [PubMed - indexed for MEDLINE]
 
75: Hanotin C, Thomas F, Jones SP, Leutenegger E, Drouin P. Related Articles
Efficacy and tolerability of sibutramine in obese patients: a dose-ranging study.
Int J Obes Relat Metab Disord. 1998 Jan;22(1):32-8.
PMID: 9481597 [PubMed - indexed for MEDLINE]
 
76: Weiser M, Frishman WH, Michaelson MD, Abdeen MA. Related Articles
The pharmacologic approach to the treatment of obesity.
J Clin Pharmacol. 1997 Jun;37(6):453-73. Review.
PMID: 9208352 [PubMed - indexed for MEDLINE]
 
77: Lean ME. Related Articles
Sibutramine--a review of clinical efficacy.
Int J Obes Relat Metab Disord. 1997 Mar;21 Suppl 1:S30-6; discussion 37-9. Review.
PMID: 9130039 [PubMed - indexed for MEDLINE]
 
78: Stock MJ. Related Articles
Sibutramine: a review of the pharmacology of a novel anti-obesity agent.
Int J Obes Relat Metab Disord. 1997 Mar;21 Suppl 1:S25-9. Review.
PMID: 9130038 [PubMed - indexed for MEDLINE]
 
79: Finer N. Related Articles
Present and future pharmacological approaches.
Br Med Bull. 1997;53(2):409-32. Review.
PMID: 9246843 [PubMed - indexed for MEDLINE]
 
80: Davis R, Faulds D. Related Articles
Dexfenfluramine. An updated review of its therapeutic use in the management of obesity.
Drugs. 1996 Nov;52(5):696-724. Review.
PMID: 9118819 [PubMed - indexed for MEDLINE]
 
81: Bray GA, Ryan DH, Gordon D, Heidingsfelder S, Cerise F, Wilson K. Related Articles
A double-blind randomized placebo-controlled trial of sibutramine.
Obes Res. 1996 May;4(3):263-70.
PMID: 8732960 [PubMed - indexed for MEDLINE]
 
82: Stanford SC. Related Articles
Stress: a major variable in the psychopharmacologic response.
Pharmacol Biochem Behav. 1996 May;54(1):211-7. Review.
PMID: 8728560 [PubMed - indexed for MEDLINE]
 
83: Ryan DH, Kaiser P, Bray GA. Related Articles
Sibutramine: a novel new agent for obesity treatment.
Obes Res. 1995 Nov;3 Suppl 4:553S-559S. Review.
PMID: 8697058 [PubMed - indexed for MEDLINE]
 
84: Weintraub M, Rubio A, Golik A, Byrne L, Scheinbaum ML. Related Articles
Sibutramine in weight control: a dose-ranging, efficacy study.
Clin Pharmacol Ther. 1991 Sep;50(3):330-7.
PMID: 1914367 [PubMed - indexed for MEDLINE]
 
86: King DJ, Devaney N. Related Articles
Clinical pharmacology of sibutramine hydrochloride (BTS 54524), a new antidepressant, in healthy volunteers.
Br J Clin Pharmacol. 1988 Nov;26(5):607-11.
PMID: 3207566 [PubMed - indexed for MEDLINE]

 

 

 

 

 

 

Accès à la Page destinée au grand-public

En attendant une étude scientifique détaillée du Sibutral sur cette page, vous pouvez déjà consulter les documents suivants :

Liste des publications contenant le mot "sibutramine" (Medline).

Liste des publications avec sibubramine dans le titre ou le résumé

Recommandation FDA pour gérer le surpoids.

Le résumé des caractéristiques de la Sibutramine sur le site de la Food and Drug Administration (pdf)

Toujours sur le site de la FDA, un complément d'informations à propos d'une étude de suivi prolongée sur 2 ans. 

Le document définitif de la FDA (pdf)

Site Knoll US

 

 Dernière mise à jour
 le 13-05-2003

  

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